Migraine

Understanding Migraine and Its Different Forms

Migraine is a neurological condition, not just a severe headache. It involves changes in brain activity and blood vessel function that produce recurring, often disabling head pain along with other symptoms like nausea and light sensitivity. Migraine comes in several distinct forms, and knowing which type you have helps guide the most effective treatment plan.

Causes

Migraine has a strong genetic component, and attacks are often set off by specific triggers:

  • Genetic predisposition: migraine frequently runs in families.

  • Hormonal changes, including the menstrual cycle and hormonal contraceptives.

  • Certain foods and drinks: alcohol (especially red wine), aged cheese, processed meats, and skipped meals are common triggers.

  • Changes in sleep: both too little and too much sleep can trigger attacks.

  • Stress, and the "let-down" period right after stress (sometimes causing weekend migraines).

  • Sensory triggers: bright or flickering lights, strong smells, and loud noise.

  • Weather or barometric pressure changes.

Types of Migraine and Their Symptoms

Migraine isn't one single condition; it has several recognized forms, each with its own pattern:

Migraine without Aura

The most common form, sometimes called "common migraine."

  • Moderate-to-severe throbbing or pulsing pain, usually on one side of the head.

  • Nausea, and sometimes vomiting.

  • Sensitivity to light and sound.

  • Pain that worsens with physical activity.

  • Untreated attacks typically last 4 to 72 hours.

Migraine with Aura

Involves temporary neurological symptoms ("aura") before or during the headache.

  • Visual disturbances: flashing lights, zigzag lines, or blind spots.

  • Numbness or tingling on one side of the body or face.

  • Difficulty speaking or finding words.

  • Aura typically lasts 20 to 60 minutes and resolves as the headache begins.

Chronic Migraine

Defined as headache on 15 or more days per month, with migraine features on at least 8 of those days, for more than 3 months.

  • Frequent, sometimes daily, headache.

  • Often develops gradually from episodic migraine over time.

  • May be worsened by overuse of acute headache medications.

Vestibular Migraine

A form of migraine with prominent dizziness and balance symptoms.

  • Episodes of vertigo or dizziness, with or without headache.

  • Imbalance or unsteadiness.

  • Increased sensitivity to motion.

Hemiplegic Migraine

A rare, more severe form of migraine with aura that can mimic a stroke, especially on its first occurrence. This needs prompt medical evaluation.

  • Temporary weakness on one side of the body, along with typical aura and headache symptoms.

  • May also involve speech or vision changes.

Menstrual Migraine

Migraine attacks linked to hormonal changes around menstruation.

  • Attacks that cluster around the start of the menstrual period.

  • Often more severe, longer-lasting, and less responsive to standard treatment than other attacks.

Red Flags: When a Headache Needs Immediate Attention

Most headaches, including migraine, are not dangerous. But certain features are warning signs that call for urgent evaluation to rule out a more serious cause:

  • The “worst headache of your life,” or a sudden “thunderclap” headache that reaches full intensity within seconds to minutes.

  • Headache with fever, stiff neck, confusion, or a rash.

  • A new headache after age 50.

  • A significant change in a long-standing headache pattern, or an entirely new type of headache.

  • Headache with neurological symptoms that don’t fully resolve: weakness, numbness, vision loss, difficulty speaking, or confusion.

  • Headache triggered by coughing, straining, or exercise.

  • Headache that worsens when lying down, or wakes you from sleep.

  • New vision changes or swelling noted in an eye exam.

  • Headache in someone who is pregnant, has cancer, or has a weakened immune system.

  • Head pain following a head injury.

Imaging Studies to Consider

For typical migraine with a stable, recognizable pattern, imaging usually isn't needed; the diagnosis is made from your history and symptoms. Imaging is reserved for atypical presentations or red-flag features:

  • MRI of the brain is used when red-flag symptoms are present, the headache pattern changes significantly, or a neurological exam finding is abnormal.

  • CT scan of the head is used urgently, like for a sudden thunderclap headache, to quickly rule out bleeding.

  • MR angiography or venography is used selectively if a blood vessel problem is suspected.

Physical Therapy, Home Exercise & Other Conservative Techniques

Lifestyle-based approaches and, when a neck component is present, physical therapy are well-studied, non-drug tools for reducing migraine frequency:

Physical Therapy

  • Treatment of a cervicogenic (neck-related) component, when neck tension contributes to attacks.

  • Postural correction, especially for those with significant screen or desk work.

  • Manual therapy and relaxation-focused techniques for the neck and shoulders.

Home Exercise Program

  • Regular aerobic exercise is one of the better-studied non-drug approaches for reducing migraine frequency.

  • A consistent, gradual approach to starting exercise, since sudden intense exertion can itself be a trigger for some people.

Other Studied Techniques

  • Keeping a consistent sleep and meal schedule, since irregularity is a common trigger.

  • A headache/trigger diary to help identify and manage personal triggers.

  • Adequate hydration.

Interventional Treatment Options

For migraine that doesn't respond well enough to standard medications, several non-opioid procedures can help:

  • Occipital nerve block: An injection of anesthetic and steroid around the nerves at the base of the skull, which can reduce migraine frequency and intensity for weeks at a time.

  • Sphenopalatine ganglion (SPG) block: Targets a nerve cluster behind the nose and can help both migraine and cluster headache.

  • Cervical trigger point or facet injections: Used when neck muscle tension or cervical facet pain is contributing to headache.

  • OnabotulinumtoxinA (Botox) injections: FDA-approved specifically for chronic migraine (15+ headache days per month); injected at multiple sites around the head and neck approximately every 12 weeks.

  • Acupuncture: A technique using thin needles at specific points; can be considered for migraine prevention, either alongside or as an alternative to preventive medication.

Neuromodulation: Spinal Cord & Peripheral Nerve Stimulation

Neuromodulation offers additional non-opioid options for migraine, from implanted devices to non-invasive wearables:

  • Occipital nerve stimulation (a form of peripheral nerve stimulation): A small electrode placed near the occipital nerves for chronic, refractory migraine that hasn't responded to other treatments.

  • Non-invasive neuromodulation devices: External devices worn on the forehead or upper arm that stimulate specific nerves without any implant, used for both treating attacks and prevention.

How Strong Is the Evidence?

A summary of the evidence supporting key treatments for migraine:

How to read this: Strong means consistent results from multiple high-quality studies. Moderate means generally favorable results with some limitations. Mixed or early means results so far are inconsistent or still emerging. Limited means few or lower-quality studies; these options can still be considered in select cases following a discussion with your healthcare provider.

  • OnabotulinumtoxinA (chronic migraine): Strong evidence. FDA-approved.

  • CGRP monoclonal antibodies: Strong evidence.

  • Triptans: Strong evidence.

  • Occipital nerve block: Moderate evidence.

  • Acupuncture: Moderate evidence.

Evidence reviewed November 2026. These ratings summarize published research and major medical society guidelines available at that time. Research continues to evolve, and we will go over the most current evidence for your situation at your visit.

Pain Psychology Techniques

Pain psychology techniques, particularly biofeedback, have some of the strongest evidence of any headache treatment:

  • Biofeedback is one of the best-studied, most effective non-drug treatments specifically for migraine.

  • Cognitive behavioral therapy (CBT) for headache helps manage triggers, stress, and the impact of migraine on daily life.

  • Relaxation training and diaphragmatic breathing.

  • Mindfulness-based stress reduction.

  • Consistent sleep habits, since irregular sleep is a common trigger.

Non-Opioid Medication Options

Migraine treatment includes both medications taken during an attack and, for frequent migraine, daily preventive medications:

Acute (abortive) treatments, taken during an attack

  • NSAIDs like ibuprofen or naproxen for mild-to-moderate attacks.

  • Triptans (like sumatriptan or rizatriptan) target serotonin receptors and are a first-line option for moderate-to-severe attacks.

  • Gepants (CGRP receptor antagonists, like rimegepant or ubrogepant) are a newer non-opioid option, including for those who can't take triptans.

  • Ditans (like lasmiditan) are another newer non-triptan option.

  • Anti-nausea medications, like metoclopramide or ondansetron, for associated nausea.

Preventive treatments, for frequent or disabling migraine

  • Beta blockers, like propranolol or metoprolol.

  • Anticonvulsants, like topiramate.

  • CGRP monoclonal antibodies, like erenumab, fremanezumab, galcanezumab, or eptinezumab; injectable medications developed specifically for migraine prevention.

  • Tricyclic antidepressants, like amitriptyline.

  • OnabotulinumtoxinA for chronic migraine prevention.

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Talk With Us About Your Options

Call 650-507-4113 or send us a message to schedule a consultation at our Daly City, Los Altos, or Stockton office. We will review what may be causing your pain and walk through the risks, benefits, and alternatives of each option with you.

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This information is provided for general patient education and does not replace individualized medical advice. Please discuss your specific symptoms, diagnosis, and treatment options with your pain management physician.

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